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Journal Papers

2024

  • Y. Zhang, W. Wu, H. Shen, J. Xu, Q. Jiang*, X. Han*,  P. Cai* . Subdiffraction Imaging of Cleared and Expanded Large-Scale Tissues. Chem. Biomed. Imaging 2024, 2, 542.

  • K. He, P. Cai, S. Ji, Z. Tang, Z. Fang, W. Li, J. Yu, J. Su, Y. Luo, F. Zhang, T. Wang, M. Wang, C. Wan, L. Pan, B. Ji, D. Li, X. Chen*. An Antidehydration Hydrogel Based on Zwitterionic Oligomers for Bioelectronic Interfacing. Adv. Mater. 2024, 36, 2311255.

  • M. Chen, Y. Li, M. Zhang, S. Ge, T. Feng, R. Chen, J. Shen, R. Li, Z. Wang, Y. Xie, D. Wang, J. Liu, Y. Lin, F. Chang, J. Chen, X. Sun, D. Cheng, X. Huang, F. Wu, Q. Zhang, P. Cai, P. Yin*, L. Zhang*, P. Tang. Histone deacetylase inhibition enhances extracellular vesicles from muscle to promote osteogenesis via miR-873-3p. Signal. Transduct. Target. Ther. 2024, 9, 256.

2023​

  • Ren X., Zhou Y., Lu F., Zhai L., Wu H., Chen Z., Wang C., Zhu X., Xie Y., Cai P., Xu J., Tang X., Li J., Yao J., Jiang Q., Hu, B.* Contact Lens Sensor with Anti-jamming Capability and High Sensitivity for Intraocular Pressure Monitoring. ACS Sensors 2023, 10, 2691.

  • Xu H., Huo Y., Zhou Q., Wang L. A., Cai P., Doss B., Huang C., Hsia K J.* Geometry-mediated bridging drives nonadhesive stripe wound healing. Proc. Natl. Acad. Sci. U. S. A. 2023, 120, e2221040120.

  • Y. Cheng, J. Xu, L. Li, P. Cai, Y. Li, Q. Jiang, W. Wang, Y. Cao, B. Xue.* Boosting the Piezoelectric Sensitivity of Amino Acid Crystals by Mechanical Annealing for the Engineering of Fully Degradable Force Sensors. Adv. Sci. 2023, 10, 2207269

2022

  • L. Liang, C. Liu, P. Cai, S. Han, R. Zhang, N. Ren, J. Wang, J. Yu, S. Shang, W. Zhou, J. Qiu, C. Mao*, X. Chen, C. Sun*, H. Liu*. Highly Specific Differentiation of MSCs into Neurons Directed by Local Electrical Stimuli Triggered Wirelessly by Electromagnetic Induction Nanogenerator. Nano Energy 2022, 100, 107483.

  • L. Zhang, X. Chen, P. Cai*, H. Sun, S. Shen, B. Guo*, Q. Jiang*. Reprogramming Mitochondrial Metabolism in Synovial Macrophages of Early Osteoarthritis by a Camouflaged Meta-Defensome. Adv. Mater. 2022, 34, 2202715.

​2021

  • J. Wang, C. Wang, P. Cai, Y. Luo, Z. Cui, X. J. Loh, X. Chen*. Artificial Sense Technology: Emulating and Extending Biological Senses. ACS Nano 2021, 33, 18671.

  • Z. Cui, W. Wang, L. Guo, Z. Liu, P. Cai, Y.Cui, T. Wang, C. Wang, M. Zhu, Y. Zhou, W. Liu, Y. Zheng, G. Deng, C. Xu, X. Chen. Haptically Quantifying Young's Modulus of Soft Materials Using a Self-Locked Stretchable Strain Sensor. Adv. Mater. 2021, 33, 2104078.

  • P. Cai, C. Wang, H. Gao*, X. Chen*. Mechanomaterials: A Rational Deployment of Forces and Geometries in Programming Functional Materials. Adv. Mater. 2021, 33, 2007977. (Front Cover)

  • J. Yu#, P. Cai#, X. Zhang, T. Zhao, L. Liang, S. Zhang, H. Liu, X. Chen*. Spatiotemporal Oscillation in Confined Epithelial Motions Upon Fluid-to-solid Transition. ACS Nano 2021, 15, 7618.

  • W. Li, N. Matsuhisa, Z. Liu, M. Wang, Y. Luo, P. Cai, G. Chen, F. Zhang, C. Li, Z. Liu, Z. Lv, W. Zhang, X. Chen*. An On-Demand Plant-Based Actuator Created Using Conformable Electrodes. Nat. Electron. 2021, 4, 134.

  • Q. Wei#, X. Shi#, T. Zhao, P. Cai, T. Chen, Y. Zhang, C. Huang, J. Yang, X. Chen, S. Zhang*. Actin-Ring Segment Switching Drives Nonadhesive Gap Closure. Proc. Natl. Acad. Sci. U. S. A. 2021, 117, 33263.

  • J. Yu, Jing, P. Cai, X. Chen*. Structural Regulation of Myocytes in Engineered Healthy and Diseased Cardiac Models. ACS Appl. Bio Mater. 2021, 4, 267.

​​2020

  • Y. Luo, M. Wang, C. Wan, P. Cai, X. J. Loh, X. Chen*, Devising Materials Manufacturing Toward Lab‐to‐Fab Translation of Flexible Electronics. Adv. Mater. 2020, 32, 2001903.

  • C. Wan#, P. Cai#, X. Guo, M. Wang, N. Matsuhisa, L. Yang, Z. Lv, Y. Luo, X. J. Loh, X. Chen*. An Artificial Sensory Neuron with Visual-Haptic Fusion. Nat. Commun. 2020, 11, 4602.

  • L. Pan, P. Cai, L. Mei, Y. Cheng, Y. Zeng, M. Wang, T. Wang, Y. Jiang, B. Ji, D. Li, X. Chen*. A Compliant Ionic Adhesive Electrode with Ultralow Bioelectronic Impedance. Adv. Mater. 2020, 32, 2003723.

  • M. Wang¶, Z. Yan¶, T. Wang, P. Cai, S. Gao, Y. Zeng, C. Wan, H. Wang, L. Pan, J. Yu, S. Pan, K. He, J. Lu, X. Chen*. Gesture Recognition Using A Bioinspired Learning Architecture that Integrates Visual Data With Somatosensory Data From Stretchable Sensors. Nat. Electron. 2020, 3, 563-570.

  • P. Cai, C. Wan, L. Pan, N. Matsuhisa, K. He, Z. Cui, W. Zhang, C. Li, J. Wang, J. Yu, M. Wang, Y. Jiang, G. Chen, X. Chen*.Locally-coupled Electromechanical Interfaces Based on Cytoadhesion-inspired Hybrids to Identify Muscular Excitation-Contraction Signatures. Nat. Commun. 2020, 11, 2183.

  • L. Ke#, P. Cai#, Y.‐L. Wu, X. Chen. Polymeric Nonviral Gene Delivery Systems for Cancer Immunotherapy. Adv. Therap.2020, 1900213.

  • L. Pan, F. Wang, Y. Cheng, W. R. Leow, Y.-W. Zhang, M. Wang, P. Cai, B. Ji, D. Li, X. Chen. A Supertough Electro-Tendon Based on Spider Silk Composites. Nat. Commun. 2020, 11, 1332.

  • S. Pan, F. Zhang, P. Cai, M. Wang, K. He, Y. Luo, Z. Li, G. Chen, S. Ji, Z. Liu, X. J. Loh, X. Chen. Mechanically Interlocked Hydrogel–Elastomer Hybrids for On‐Skin Electronics. Adv. Funct. Mater. 2020, 1909540.

  • B. Hu, C. Berkey, T. Feliciano, X. Chen, Z. Li, C. Chen, S. Amini, M. H. Nai, Q.‐L. Lei, R. Ni, J. Wang, W. R. L., S. Pan, Y.‐Q. Li, P. Cai, A. Miserez, S. Li, C. T. Lim, Y.‐L. Wu, T. W, Odom, R. H. Dauskardt, X. Chen. Thermal‐Disrupting Interface Mitigates Intercellular Cohesion Loss for Accurate Topical Antibacterial Therapy. Adv. Mater. 2020, 32, 1907030.

​​2019

  • P. Cai, X. Chen. Hydrogels for Artificial Vitreous: From Prolonged Substitution to Elicited Regeneration. ACS Mater. Lett. 2019, 1, 285.

  • P. Cai,  Z. Li, L. Wang, C. Wan, Y. Jiang, B. Hu, Y.‐L. Wu, S. Wang, C. T. Lim, E. Makeyev, S. Magdassi, X. Chen. Differential Homeostasis of Sessile and Pendant Epithelium Reconstituted in a 3D-Printed “GeminiChip”. Adv. Mater. 2019,31, 1900514.

  • C. Wan, P. Cai, M. Wang, Y. Qian, W. Huang, X. Chen. Artificial Sensory Memory. Adv. Mater. 2019, 31, 1902434.

  • M. Wang, T. Wang, P. Cai, X. Chen. Nanomaterials Discovery and Design through Machine Learning. Small Methods 2019,3, 1900025.

  • S. Bai, X. Zhang, P. Cai, X. Huang, Y. Huang, R. Liu, M. Zhang, J. Song, X. Chen, H. Yang. A Silk-based Sealant with Tough Adhesion for Instant Hemostasis of Bleeding Tissues. Nanoscale Horizons 2019, 4, 1333-1341.

  • J. Yu, J. Kong, W. Hao, X. Guo, H. He, W. R. Leow, Z. Liu, P. Cai, G. Qian, S. Li, X. Chen, X. Chen. Broadband Extrinsic Self-Trapped Exciton Emission in Sn-Doped 2D Lead-Halide Perovskites. Adv. Mater. 2019, 31, 1806385.

​​2018

  • P. Cai, B. Hu, W. R. Leow, X. Wang, X. J. Loh, Y.-L. Wu, X. Chen. Biomechano-Interactive Materials and Interfaces. Adv. Mater. 2018, 30, 1800572.

  • P. Cai, X. Zhang, M. Wang, Y.-L. Wu, X. Chen. Combinatorial Nano-Bio Interfaces. ACS Nano 2018, 12, 5078.

  • L. Wang, P. Cai, J. Luo, F. Zhang, J. Liu, Y. Chen, Z. Zhu, Y. Song, B. Yang, X. Liu, X. Chen, S. Wang. Engineering Subcellular-Patterned Biointerfaces to Regulate the Surface Wetting of Multicellular Spheroids. Nano Res. 2018, 11, 5704-5715.

  • G. Chen, N. Matsuhisa, Z. Liu, D. Qi, P. Cai, Y. Jiang, C. Wan, Y. Cui, W. R. Leow, Z. Liu, S. Gong, K.-Q. Zhang, Y. Cheng, X. Chen. Plasticizing Silk Protein for On-Skin Stretchable Electrodes. Adv. Mater. 2018, 30, 1800129. 

  • X. Chen, Z. Chen, B. Hu, P. Cai, S. Wang, S. Xiao, Y.-L. Wu, X. Chen. Synergistic Lysosomal Activatable Polymeric Nanoprobe Encapsulating pH-Sensitive Imidazole Derivative for Tumor Diagnosis. Small 2018, 14, 1703164.

  • T. Wang, H. Yang, D. Qi, Z. Liu, P. Cai, H. Zhang, X. Chen. Mechano-Based Transductive Sensing for Wearable Healthcare. Small 2018, 14, 1702933.

  • M. Wang, W. Wang, W. R. Leow, C. Wan, G. Chen, Y. Zeng, J. Yu, Y. Liu, P. Cai, H. Wang, D. Ielmini, X. Chen. Enhancing the Matrix Addressing of Flexible Sensory Arrays by A Highly Nonlinear Threshold Switch. Adv. Mater. 2018, 30, 1802516.

  • B. Li, Y. Liu, C. Wan,Z. Liu, M. Wang, D. Qi, J. Yu, P. Cai, M. Xiao, Y. Zeng, X. Chen. Mediating Short-Term Plasticity in an Artificial Memristive Synapse by the Orientation of Silica Mesopores. Adv. Mater. 2018, 30, 1706395.

​​2017

  • P. Cai, W. R. Leow, X. Wang, Y.-L. Wu*, X. Chen*. Programmable Nano-Bio Interfaces for Functional Biointegrated Devices. Adv. Mater. 2017, 29, 1605529. (ESI highly-cited; Inside Back Cover)

  • B. Hu, W. R. Leow, P. Cai, Y.-Q. Li, Y.-L. Wu, X. Chen*. Nanomechanical Force Mapping of Restricted Cell-to-Cell Collisions Oscillating Between Contraction and Relaxation. ACS Nano 2017, 11, 12302-12310.

  • Y.-L. Wu, W. Engl, B. Hu, P. Cai, W. R. Leow,N. S. Tan, C. T. Lim, X. Chen. Nanomechanically Visualizing Drug–cell Interaction at The Early stage of Chemotherapy. ACS Nano 2017, 11, 6996-7005.

  • B. Hu, W. R. Leow, R. Amini, B. Nai, X. Zhang, Z. Liu, P. Cai, Z. Li, Y.-L. Wu,A. Miserez, C. T. Lim, X. Chen. Orientational Coupling Locally Orchestrates a Cell Migration Pattern for Re-Epithelialization. Adv. Mater. 2017, 29, 1700145.

​​2016

  • P. Cai, M. Layani, W. R. Leow, S. Amini, Z. Liu, D. Qi, B. Hu, Y.-L. Wu, A. Miserez, S. Magadassi, X. Chen. Bio-Inspired Mechanotactic Hybrids for Orchestrating Traction-Mediated Epithelial Migration. Adv. Mater. 2016, 28, 3102.

​​2015

  • A. Tijore, P. Cai, M. H. Nai, Z. Li, Y. Wang, C. Y. Tay, C. T. Lim, X. Chen, L. P. Tan. Role of Cytoskeletal Tension in The Induction of Cardiomyogenic Differentiation in Micropatterned Human Mesenchymal Stem Cell. Adv. Healthc. Mater. 2015,4, 1399-1407.

  • C. T. Tay, Y.-L. Wu, P. Cai, N. S. Tan, S. Venkatraman, X. Chen, L. P. Tan. Bio-inspired Micropatterned Hydrogel to Direct and Deconstruct Hierarchical Processing of Geometry-Force Signals by Human Mesenchymal Stem Cells During Smooth Muscle Cell Differentiation. NPG Asia Mater. 2015, 7, e199.

  • Y. Yuan, Z. Wang, P. Cai, J. Liu, L.-D. Liao, M. Hong, X. Chen, N. Thakor, B. Liu. Conjugated Polymer and Drug Co-encapsulated Nanoparticles for Chemo-and Photo-Thermal Combination Therapy with Two-photon Regulated Fast Drug Release. Nanoscale 2015, 7, 3067-3076.

  • G. Jin, D. Mao, P. Cai, R. Liu, N. Tomczak, J. Liu, X. Chen, D. Kong, D. Ding, B. Liu, K. Li*. Conjugated Polymer Nanodots as Ultrastable Long‐Term Trackers to Understand Mesenchymal Stem Cell Therapy in Skin Regeneration. Adv. Funct. Mater. 2015, 25, 4263-4273.

​​2014

  • C. Y. Tay#, P. Cai#, M. Setyawati, W. Fang, L. P. Tan, C. Hong, X. Chen*, D. T. Leong*. Nanoparticles Strengthen Intracellular Tension and Retard Cellular Migration. Nano Lett. 2014, 14, 83–88.

  • B. Hu, W. Shi, Y.-L. Wu, W. R. Leow, P. Cai, S. Li, X. Chen. Orthogonally Engineering Matrix Topography and Rigidity to Regulate Multicellular Morphology. Adv. Mater. 2014, 26, 5786-5793.

  • S. Yin, Y.-L. Wu, B. Hu, Y. Wang, P. Cai, C. K. Tan, D. Qi, L. Zheng, W. R. Leow, N. S. Tan, S. Wang, X. Chen. Three-Dimensional Graphene Composite Macroscopic Structures for Capture of Cancer Cells. Adv. Mater. Interface 2014, 1,1300043.

  • K. Li, Z. Zhu, P. Cai, R. Liu, N. Tomczak, D. Ding, J. Liu, W. Qin, Z. Zhao, Y. Hu, X. Chen, B. Z. Tang, B. Liu. Organic Dots with Aggregation-Induced Emission (AIE dots) Characteristics for Dual-Color Cell Tracing. Chem. Mater. 2014, 25, 4181-4187.

2013

  • C. R. I. Lam, C. Tan, Z.Teo, C. Y. Tay, T. Phua, Y.-L. Wu, P. Cai, L. P. Tan, X. Chen, P.  Zhu, N. S. Tan. Loss of TAK1 Increases Cell Traction Force in A ROS-dependent Manner to Drive Epithelial–Mesenchymal Transition of Cancer Cells. Cell Death Dis. 2013, 4, e848.

  • Y. Jiang, F. Meng, D. Qi, P. Cai, Z. Yin, F. Shao, H. Zhang, F. Boey, X. Chen. Gold Nanotip Array for Ultrasensitive Electrochemical Sensing and Spectroscopic Monitoring. Small 2013, 9, 2260-2265.

2011

  • J. Guo, Y. Wei, D. Zhou, P. Cai, X. Jing, X.-S. Chen, Y. Huang. Chemosynthesis of Poly (ε-lysine)-Analogous Polymers by Microwave-Assisted Click Polymerization. Biomacromolecules 2011, 12, 737-746.

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